Symptoms of Purpura Nephritis

Symptoms of Purpura Nephritis
Purpura nephritis is very common in children, but many people in any ages can be affected. For purpura nephritis is liable to impair kidneys, patients should prevent or block its coming after they have had HSP. So some knowledge about symptoms of purpura nephritis is essential for patients who have had HSP or been at the risk.
The primary symptoms of HSP are purpura, arthritis and abdominal pain, which are bound to appear as a trilogy.
The purple rashes are caused by the bleeding of the capillary in skin, which are presented as small purple spots primarily developing into big or large sheets. Some of the purple rashes are swelling and higher than skin surface. They are spread all over in the body, especially in the face, neck, buttocks and legs.
The arthritis can affect many joint, such as elbow, knees, spine and ankle. When abnormal immune system flares in the joint, the cartilages between the bones are broken down, resulting in joint pain, swelling (inflammation) and stiffness.
Abdominal pain is characterized by a colicky pain, and sometimes may be accompanied by nausea, vomiting and bloody stools. The vasculitis caused by SHP may lead to the swelling of gut, resulting in serious and intermittent pain sometimes due to the intussusceptions (especially in children).
The vasculitis caused by HSP is vital to the damage of renal function. Hematuria and proteinuria are the main signs to predict that inflammation appear in the kidney tissue and destruction takes place. Almost 40% of patients with SHP involve in the kidney disease.
Most patients have evidence of blood in urine (hematuria); while only one forth of patients has this symptom which is not noticeable without special tests. More than half of patients also have proteinuria. If patients miss the best time to treat, the condition may develop more serious. One eight of patient may progress to nephrotic syndrome which is marked by protein in urine, swelling, high cholesterol levels and low blood protein.
All above are the most symptoms of purpura nephritis which is a process that disordered immune system causes a series of vasculitis disease and develops more serious to affect the renal function. Patients should grasp the best time to have an effective treatment in the early stage. Otherwise, the worst stage, uremia may be coming soundlessly. If you have some symptoms, please consult us online.